CTSI Innovation - Innovation Portfolio
PI: Ellen Beckjord
Project Description: A tool for smoking cessation support
Project Description: At-home therapy to heal diabetic skin ulcers
Project Description: Parkinson's disease-focused app support patient independence
Project Description: A Cloud-based application to decrease hospital readmission
Project Description: A peer-staffed text helpline for teens with sexual health questions
Project Description: Improving compliance and safety
PI: Kevin Bell
Project Description: Device for monitoring PT after ACL reconstruction
Project Description: Breathalyzer for measuring acetone for patients in ketosis
Project Description: “Game” to guide children using a nebulizer
Project Description: Telemedicine and patients history in pediatric cancer survivors
Project Description: Monitoring medication adherence in schizophrenia patients and other mental health disorders
Project Description: Video series for education of pediatric patients/families
Project Description: Measuring metabolic marker in treatment resistant depression
PI: Yadong Wang
Project Description: The Phoenix bio-inductive vascular graft combines the wide applicability of an off-the-shelf prosthetic graft with the in vivo performance of an arteriovenous fistula.
PI: Michael Balsan
Project Description: NEATCAP is a hearing protection device for babies in neonatal intensive care units that blocks noxious noise, and promises to reduce infant stress, improve sleep, and promote brain development.
PI: Xinyan Tracy Cui
Project Description: At OXI-DENT we are a team of bioengineering and chemical engineering graduate students from the University of Pittsburgh that developed a coating to solve the problem of dental implant inflammation.
PI: Jeffrey Gusenoff
Co-I: Beth Gusenoff
Project Description: FeetForLife uses your own fat to cushion your painful feet so you can walk for a lifetime with less pain and suffering.
PI: Volker Musahl
Co-I: Richard Debski
Project Description: This technology quantifies the pivot shift test that evaluates knee ligamentous injuries. The pivot shift test is associated with future development of osteoarthritis in these patients.
PI: Judy Cameron
Co-I: Jeanette Trauth
Project Description: This is an intergenerational program where senior citizens and preteen youth partner to provide preschool children in underserved communities with critical skills for school success.
PI: Robert Powers
Project Description: A safe, simple and inexpensive nutraceutical intervention (Citrulline) given in early pregnancy to lower blood pressure and improve placentation.
PI: Maliha Zahid
Project Description: A novel peptide for delivering radioisotopes, therapeutic small molecules or proteins specifically to heart muscle.
PI: Stephen Badylak
Project Description: Minimally invasive treatment for Barrett´s Esophagus causing disease regression and mitigation of cancer risk.
PI: Bryan Brown
Project Description: For those seeking better ways to treat and recover from nerve injuries, NeuroGel is an injectable solution that provides a simple and effective method for enhancing nerve reconstruction.
PI: Christopher Wilmer
Project Description: This portable oxygen device uses porous materials to store medical oxygen at low pressure in a standard 12oz aluminum can—making oxygen therapy more portable than ever before!
PI: David Rabin
Project Description: Purrr is a convenient, wearable, and intuitive tool that detects stress on the rise and empowers you to effortlessly control it before it controls you.
PI: Robert Shanks
Project Description: A new generation of eye drops that allow current advanced biological drugs to act on the surface of the eye.
PI: Amit Sethi
Project Description: I-HITS is an individualized hand improvement and tracking system, which allows patients with stroke to monitor their hand movement and enables therapists to deliver treatment outside therapy.
PI: Prashant Kumta
Project Description: VasoMag is a novel engineered biodegradable metallic vascular stent technology that provides superior mechanical support to open the narrowed vessels and maintain the needed patency while safely degrading in 6-12 months.
PI: Youngjae Chun
Project Description: A ventriculo-amniotic shunt to treat fetal hydrocephalus will prevent the progressive brain injury that occurs in utero until conventional treatment can be instituted following birth.
PI: Kelly Beck
Project Description: Continuously track potential environmental triggers and prodromal symptom activity in chronic migraineurs to better define the therapeutic window.
PI: Bethany Barone Gibbs
Project Description: In low back pain sufferers, breaking up prolonged sitting with a height adjustable desk and an activity monitor that prompts movement, may increase adherence to activity and decrease pain.
PI: Sarah Ross
Project Description: A hallmark of chronic pain is that nociceptive input from the periphery becomes abnormally amplified in the spinal cord through wind-up. Our studies will provide novel mechanistic insight into wind-up
PI: Michael Gold
Project Description: Over thirty million North Americans suffer from irritable bowel syndrome which takes a tremendous societal toll due to the absence of effective treatments for the pain associated with this disorder.
PI: Paul Kinchington
Project Description: TRIgeminal Pain and Ocular Neurological Disease models for varicella Zoster virus, which causes Shingles, post herpetic neuralgia and devastating blinding disease.
PI: Jeff Gusenoff
Project Description: A novel incisionless approach to perforating the plantar fascia and fill it with fat to allow elongation, regeneration, and pain elimination.
PI: Marianne Seney
Project Description: Evaluating the molecular and genetic mechanisms that link chronic pain resulting from depression and/or anxiety.
PI: Grace Lim
Project Description: Pain during childbirth is related to risk for postpartum depression. Current epidural strategies ignore the potential utility of more aggressive pain management for mothers at risk for depression.
PI: James Ibinson
Project Description: Refinement of our brain imaging technique will provide an objective biomarker able to reflect the cognitive process of pain perception, facilitating improved understanding and treatment of pain.
PI: Sarah Ross
Project Description: A novel kappa opioid receptor antagonist to reduce both the aversive as well as the nociceptive components of pain.
PI: Matt Kostek, Eric Helm
Project Description: An integrative approach combining two known analgesic interventions (exercise & meditation) in a novel interaction study to treat patients with chronic pain.
PI: Maria Pacella
Project Description: Early psychological intervention (i.e., PTSD Coach app) to help reduce post-injury maladaptive psychological processes and thereby prevent post-injury chronic pain.
PI: Christina Mair
Project Description: By studying local access to medical marijuana in California, we will determine how a safer alternative may curb the skyrocketing opioid epidemic in Pennsylvania.
PI: Phil Empey
Project Description: A patient-centered smartphone application that makes it easy for patients to update and share medication lists. Personal medication coach, reminders, and links to key facts and educational videos.
PI: Liza Villaneueva
Project Description: Patented polymer microbubble contrast agent for x-ray darkfield imaging provides tissue structure information and a non-nephrotoxic alternative to iodinated contrast in diagnostic radiography.
PI: Yadong Wang
Project Description: A reverse thermal gel that is a highly effective controlled release formula for cargo molecules. A reverse thermal gel dissolves in water at lower temperatures and undergoes spontaneous phase transition with increasing temperature to form a solid gel at elevated temperatures.
PI: Chris Seymour
Project Description: a wireless, sepsis alert tool for prehospital patients and providers, embedded within a secure EMS Navigator application, developed with principles of user-centered design and empirically validated scientific content.
PI: Stuart Mendenhall
Project Description: A finger ring sensor that measures pulse-ox, galvanic skin resistance, EKG, and temperature.
PI: Rachel Berger
Project Description: A serum test to evaluate biomarkers correlated to head trauma
PI: John Kellum
Project Description: A smartphone/computer application to empower patients recovering from acute kidney injury to monitor medications and easily interpret creatinine levels to personalize their care.
PI: Dana Rofey
Project Description: eHealth Mobile Technology Connecting Young Adults to Routine Engagement (eMCARE) is a communication technology that connects young adults presenting in the emergency department to primary care by using innovative mobile, rewards-based text messaging application.
PI: William Wagner
Project Description: A polyurethane, fibrous, stentless or stented tri-leaflet valve that is non-thrombogenic, capable of mimicking native valve mechanics, micro-structure, anatomy and function in all positions, where the polyurethane core is replaced over time by functional host tissue without calcifying.
PI: Kata Himes
Project Description: An innovative tool to improve compliance with postpartum care – a critical period when health care providers can influence the lives of moms and babies for years to come.