Additional Informatics Resources
A range of informatics resources including training is available to investigators at the University of Pittsburgh:
Pitt Biomedical Informatics Training
Biomedical informatics is the interdisciplinary field that studies and pursues the effective uses of biomedical data, information, and knowledge for scientific inquiry, problem solving and decision making, motivated by efforts to improve human health. The Pitt Biomedical Informatics Training Program provides a strong foundation in the fundamentals of data science and artificial intelligence, and advanced research and training in many disciplines of biomedical informatics, including clinical informatics, population informatics, clinical research informatics, bioinformatics, imaging informatics, and environmental informatics. This program offers graduate training for certificate, master’s, and doctoral study and offers predoctoral and postdoctoral positions that are funded by a T15 grant from the National Library of Medicine. For more information, visit the Department of Biomedical Informatics website.
Center for Causal Discovery (CCD)
The Center for Causal Discovery (CCD) was founded in 2014 as an NIH Big-Data-to-Knowledge (BD2K) Center of Excellence, with the goal of developing and disseminating computational methods for causal discovery to support an ongoing process of scientific experimentation, data analysis, and discovery. The Center seeks to develop statistical and computational methods that can extract as much causal knowledge as possible from big data and provides research, training, workshops, and software to investigators. For more information, visit the CCD website.
MIDAS Information Services Group
Funded by NIGMS the MIDAS (Models of Infectious Disease Agent Study) Information Services Group (ISG) develops informatics methods, services, and systems to catalyze scientific research in infectious disease epidemiology. Other current research projects include developing and validating of a Bayesian outbreak detection and characterization system including the ability to detect and characterize concurrent outbreaks and outbreaks of unknown diseases; and developing of a standard vocabulary for the field of epidemic modeling. For more information, visit the MIDAS ISG website.
Center for Clinical Research Informatics (CCRI)
The Center for Clinical Research Informatics is a core informatics center in the Department of Biomedical Informatics that is focused on the application of informatics for the reuse of clinical, mobile health, molecular and research data to enable clinical, translational, and informatics research. In particular, CCRI is focused on developing ontologies, terminologies and data characterization; data sharing in federated networks; and data management for precision medicine. For more information, visit the CCRI website.
Center for Clinical Informatics (CCI)
The Center for Clinical Informatics (CCI) is a core informatics center in the Department of Biomedical Informatics that is focused on the application of informatics to deliver healthcare services that include developing intelligent electronic medical record systems, personalized modeling for precision medicine, developing decision support using wearable technology and mobile health applications, developing genomics and pharmacogenomics decision support, and developing a knowledgebase of drug-drug interactions for decision support. For more information, visit the CCI website.
Precision Medicine Initiative – All of Us Research Program
The All of Us Research Program is a landmark longitudinal research effort that aims to engage 1 million or more U.S. participants to revolutionize how disease is prevented and treated based on individual differences in lifestyle, environment and genetics. The University of Pittsburgh is funded as one of the enrollment sites and will enroll 150,000 participants and will collect questionnaire data, electronic medical record data, bio specimens and mobile health data for these participants. For more information, visit the All of Us Research Program website.
PaTH Clinical Data Research Network
PaTH is a Patient Centered Outcomes Research Institute (PCORI) Clinical Data Research Network project, which is focused on building a federated clinical data research network for the Mid-Atlantic region. It is comprised of Geisinger Health System, Johns Hopkins University, Johns Hopkins Health System, Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Temple Health System, Lewis Katz School of Medicine at Temple University, the University of Pittsburgh, UPMC, the University of Utah, and University of Utah Health Care. The University of Pittsburgh leads the informatics component of PaTH. The goal of PaTH is to identify and share data on three targeted conditions (idiopathic pulmonary fibrosis, atrial fibrillation and obesity) across six institutions and nationally. For more information, visit the PaTH website.
Accrual of patients to Clinical Trials (ACT) network
The ACT network is a nationwide network of sites that share electronic medical record data to significantly increase participant accrual to the nation’s highest priority clinical trials. The current ACT network consists of 21 CTSA institutions and the goal is to expand the network to all CTSA institutions. For more information, visit the ACT website.
National Mesothelioma Virtual Bank (NMVB)
The National Mesothelioma Virtual Bank (NMVB) is a virtual biospecimen registry designed to support and facilitate basic science, clinical, and translational research that will advance understanding of mesothelioma pathophysiology with the goal of expediting the discovery of preventive measures, novel therapeutic interventions, and ultimately, cures for mesothelioma. For more information, visit the NMVB website.
Center for Commercial Applications of Healthcare Data (CCA)
The Center for Commercial Applications of Healthcare Data (CCA) was formed as part of the Pittsburgh Health Data Alliance (PHDA) Initiative in July, 2015. The PHDA is a collaboration among UPMC, University of Pittsburgh, and Carnegie Mellon University aimed at cultivating translational research projects that intersect major unmet healthcare needs for purposes of commercial translation. Successful commercial translation of basic and clinical research reframed around unmet healthcare needs will expand the impact of Pitt’s research efforts through improved health and more efficient healthcare spending. The CCA operations are led by sciVelo, a new University of Pittsburgh Health Sciences program with a transdisciplinary team of academic, clinical and business leaders with deep expertise and passion for commercial translation. For more information, visit the CCA website.